12/27/2023 0 Comments Neoprobe sentinel node biopsy![]() Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Giuliano AE, Kirgan DM, Guenther JM, Morton DL. Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Krag DN, Weaver DL, Alex JC, Fairbank JT. Minimal-access surgery for staging of malignant melanoma. Technical details of intraoperative lymphatic mapping for early stage melanoma. Diagnosis of axillary lymph node metastases in patients with breast cancer. Prediction of axillary lymph node status in breast cancer patients by use of prognostic indicators. Ravdin PM, De Laurentiis M, Vendely T, Clark GM. Predicting axillary lymph node metastases in breast carcinoma patients. ![]() J Am Coll Surg 1996 183:185–9.Ĭhoong PL, deSilva CJS, Dawkins HJS, et al. Incidence and predictors of axillary metastases in T1 carcinoma of the breast. Giuliano AE, Barth AM, Spivack B, Bietsch PD, Evans SW. Role of axillary dissection in breast cancer management. Axillary lymph nodes and breast cancer: a review. Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation. Ann Surg Oncol 1996 3:235–40.įisher B, Redmond C, Fisher ER, et al. Clinical behavior of untreated axillary nodes after local treatment for primary breast cancer. J Am Coll Surg 1996 183:262–4.īaxter N, McCready D, Chapman JA, et al. Enhancing the accuracy for predictors of axillary nodal metastasis in T1 carcinoma of the breast: role of selective biopsy with lymphatic mapping. The SLN was positive in all women with axillary metastases (negative predictive value, 100%).Ĭonclusions: If confirmed by larger series, a negative SNB may eliminate the need for ALND for select women with breast cancer. Fifteen of 42 (36%) patients had lymph node metastases. SLN localization rate and predictive value were the same for women who had and those who had not undergone excisional biopsy before the date of SNB. Results: An axillary SLN was found in 38 of 42 (90%) cases. The histologic findings of the axillary contents and SLN were compared. The SLN was excised separately, and a level I/II ALND was completed. Intraoperatively, the SLN was identified using a gamma detector (Neoprobe 1000) or by visualization of the blue-stained lymph node and afferent lymphatics. Sixty to 90 minutes before anesthetic induction, a mixture of 3 mL ISB and 1 mCi TSC was injected around the primary cancer or prior biopsy site. Methods: Forty-two women with T1 or T2 breast cancer underwent SNB and ALND. This study assessed the success and accuracy of axillary SNB with isosulfan blue (ISB) and technetium-99 sulfur colloid (TSC) compared to ALND. Background: Sentinel lymph node biopsy (SNB) in breast cancer may be used in place of axillary lymph node dissection (ALND) if SNB accurately stages the axilla.
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